These include drug concentration and number and timing of doses to ensure efficacy while minimizing potential off-target effects, as well as toxicity and safety issues. Historically, oligonucleotide q...
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HPLC peak areas and their corresponding OD260 values. Oligodeoxynucleotides (ODNs) are typically purified and analysed with HPLC equipped with a UV-Vis detector. Quantities of ODNs are usually...
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The application of this novel FI–SPR device for sequence‐specific ultratrace analysis of oligodeoxynucleotides (ODNs) and polydeoxynucleotides was demonstrated. Self‐assembled
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Oligodeoxynucleotides (ODNs) are typically purified and analysed with HPLC equipped with a UV-Vis detector. Quantities of ODNs are usually determined using a UV-Vis spectrometer separately after
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Oligodeoxynucleotides are synthesized by Genset (Evry, France). Purification and quality control are ascertained by PAGE, anion-exchange HPLC, mass spectrometry, 1 H-NMR, total enzymatic digest,
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These include drug concentration and number and timing of doses to ensure efficacy while minimizing potential off-target effects, as well as toxicity and safety issues.
Quantities of ODNs are usually determined using a UV-Vis spectrometer separately after HPLC, and are reported as optical density at 260 nm (OD260). Here, we describe a method for direct determination
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Optical density is a measure used for filters to describe how much light of a blocked wavelength still passes the filter. Abbreviation: ODn. The optical density is an input value, demanded by the
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Oligodeoxynucleotides (ODNs) are typically purified and analysed with HPLC equipped with a UV-Vis detector. Quantities of ODNs are usually determined using a UV-Vis spectrometer separately...
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